on all orders above $300.00

FREE Pills!


for free with every order



Less than in your
local pharmacy

Search by letter:


Enter coupon: (if you have one)

Clofranil (Clomipramine)

Clofranil is used to treat the excessive and repetitive ideas, thoughts, and impulses of obsessive-compulsive disorder. It’s most often used when obsessions and compulsions cause you major distress and interfere with your work or social life.

Other names for this medication:
Clomipramine, Anafranil, Clofranil, Clomipramina, Clora, Zenil,

Similar Products:
Telviran, Cefakind, Aversan, Ceftas, Amoval, Depaxil, Fimoxyclav, Aurene, Epivir, Pladex, Duricef, Bagovir, Panpac, Talavir, Endoxan, Zitrotek, Degastrol, Symasteride, Miol, Tofranil, Sertima, Bactricid, Vermazol, Neurontin, Valax, Prozac, Citrol, Oxactin, Clarimac, Copegus, Metrozol, Dulane, Orlica,

clofranil clomipramine hydrochloride for dogs

We show that the micro RNAs closely follow the patterns of protein evolution in the Hox clusters, which is characterized by cluster duplications followed by differential gene loss. Mice immunized with whole blood cells loaded with mRNA encoding antigen develop anti-tumor immunity comparable to DC-RNA immunization.

clofranil medicine dictionary

Pain improvement was checked with a Visual Analogue Scale (VAS) and their disability was evaluated with the Oswestry Disability Index. Tap water consumers differ from non-consumers in chlorine flavor acceptability but not sensitivity. Our series presents the use of a novel intraoperative navigational system that uses a skull-mounted tracker to navigated anterior skull base surgery.

clofranil tablets 10mg lortab

For selected patients, avoiding admission through provision of hospital care at home yielded similar outcomes to inpatient care, at a similar or lower cost. Histologically the carcinoma is composed of lobular arranged solid and cribrous cell formations only separated by a sparse fibrous stroma.

clofranil 25 mg uses

The reason for the observed sensorineural component of the hearing loss at this age is not clear, since endocochlear potentials were normal in mice of this strain. The evidence was then used as the basis for recommendations about the diagnosis of tuberculosis disease and LTBI in adults and children. In recent years, comprehensive geriatric assessment (CGA), which has been developed as a multidimensional evaluation method for the elderly, has been attracting attention for cancer care as well. The factor decreased the fibrinogen content of plasma as well as the activity of coagulation factors V, VIII and IX but not factor VII, X or XI activities. Can age-based estimates of weight be safely used when resuscitating children?

clofranil medicine

Diffusion-weighted MR imaging is generally thought to be highly sensitive for the diagnosis of acute stroke. Manipulation of a conspicuous predator, the ant Solenopsis invicta, revealed a negative effect on numbers of P. DNA 5-cytosine methyltransferase enzymes (DCMTases) catalyze cytosine methylation via reaction intermediates in which the DNA is drastically remodeled, with the target cytosine residue extruded from the DNA helix and plunged into the active site pocket of the enzyme.

clofranil tablets at best

Besides the combination of metal-ligand binding, base pair interactions and peptide stacking interactions, in the last few years, hybridized synthetic foldamers have proven to be useful in this context. palmetto promoting both seed escape from predators and seedling vigor. Neurological complications following the use of continuous extradural analgesia with bupivacaine. Incubation with 2 agents that induce endoplasmic reticulum stress, tunicamycin and thapsigargin, increased TRB3 levels in normal cells.

clofranil tablets side effects

Curative effect of 3D-CRT combined with gemcitabine concurrently with addition of Kanglaite Injection in treatment of locally advanced pancreatic The review included all case reports, letters and original articles reporting any treatment for palmoplantar lichen planus but not treatment used in the other type of lichen planus, generalized lichen planus or other type of palmoplantar dermatoses. These results allow for the possibility of balanced selection between the reference and Kilifi forms of ICAM-1 through modulation of inflammatory responses and indicate the existence of differences within ICAM-1-binding P. Efforts should be made to identify the cause of this true increase. General expectations as regards physician-patient communication are more important for patients than other more specific ones.

clofranil drug testing

Limited treatment options have been available for people with HIV who have had virological failure of the three original classes of HIV antiretroviral drugs-so-called triple-class virological failure (TCVF). These results demonstrated that cholic acid/PEI-assembled positive nanoparticles may function as cost-effective and locally applicable or injectable nanohemostats for hemorrhage control in the civilian setting and on the battlefield. Dynamic evanescent phonon coupling across the La(1-x)Sr(x)MnO3/SrTiO3 interface.

clofranil sr side effects

Hypotheses include controlling endolymphatic fluid homeostasis and inner ear immunological defense. In two patients receiving intravitreal Ozurdex implant injection, a rare complication of fracture of implant was noted immediately after the injection. According to the EU Directive 2000/60/EC (Water Framework Directive, hereinafter called: WFD), several steps have to be worked out on the way towards the good water status. Infection of a hip prosthesis is one of the most severe complications encountered in orthopedic practice.

clofranil clomipramine hydrochloride msds

c-Jun NH2-terminal kinase regulates lipopolysaccharide-induced pulmonary mononuclear cell recruitment via CCL2. Lung and skin enzymes also showed similar affinity for both substrates, which differed however from that of liver and kidney UDPGDH. Reinterventions in postoperative instability of the lumbar spine ORTI: An Open-Access Repository of Transcriptional Interactions for Interrogating Mammalian Gene Expression Data.

clofranil medicine shoppe

Even when linguistic processing demands were controlled, planning either type of action was associated with asymmetrical increases in the same regions of left parietal (the intraparietal sulcus, supramarginal gyrus, and caudal superior parietal lobule) and dorsal premotor cortices. This research emphasizes a need for specialized training in counseling programs for alcohol counselors. The purpose of the current study was to determine whether seasonality and neuroticism are actually the same construct given that they are both associated with the same genetic polymorphism. The respective alpha beta and gamma delta T-cell receptors (TCRs) are encoded by somatically rearranged genes. Effect of toxins of cyanobacteria of the Microcystis genus from the Shershnevo Reservoir on DNA, cell cycle, and apoptosis of bone marrow cells in CBA mice

clofranil tablets 10mg diazepam

To evaluate the effect of high permeability haemodialysis (HPHD) against conventional haemodialysis (CHD) on UP. As a result of the accuracy of these MRI examinations and their remarkable similarity with the pathological specimens, which was shown to be statistically significant (P less than 0,005), we propose a modification to the sequence of the diagnostic staging modalities for musculoskeletal tumours.

clofranil clomipramine hydrochloride for people

Scientific efforts have been directed primarily toward maximizing the benefits of OCs--which remain the most effective, reversible form of birth control--while minimizing their potential risks, specifically thromboembolic disorders and cardiovascular disease. Lymphocele is a rare cause of impairment of graft function after renal transplantation. Advances in optical imaging modalities and the continued evolution of genetically-encoded fluorescent proteins are coming together to facilitate the study of cell behavior at high resolution in living organisms. These new understanding of the role of HSPs provides useful clues for the diagnosis and treatment of atherosclerosis.

clofranil tablets walmart

There is growing evidence of emerging resistance by Pneumocystis jirovecii (the species that infects humans) to TMP-SMX associated with mutations in the targeted enzymes. Its potential roles are discussed, and a new diagnostic algorithm is proposed. Side-effect checklists will be used to monitor the adverse events at each visit. Aromatic hydroxylation in PBN spin trapping by hydroxyl radicals and cytochrome P-450. Hydrogen peroxide (H2O2) is an important chemical commodity, with demand growing significantly in chemical synthesis due to its green characteristics.

clofranil 50 mg to g

The high rates of alcoholism and functional psychosis found in referred patients probably reflect the increased prevalence of these conditions in the general community. Purpose of this study was to characterize the localization and time course of contrast enhancement of a nanoparticular alkaline earth metal-based contrast agent (VISCOVER ExiTron nano) developed for small animal liver CT imaging. The use of DNA fingerprinting to assess monozygotic twinning in Meishan and Landrace x large white pigs.

clofranil tablets side effects

None of these fractions was detected in the urine of 20 controls. Linear regression was used to evaluate the relationship between gestational age at delivery and total charges. A facile fabrication of amphiphilic Janus and hollow latex particles by controlling multistage emulsion polymerization. Conversely, gender has a significant influence on the susceptibility to certain adverse effects, not the least those involving alterations in sex hormone metabolism.

clofranil drug information

The number of antibodies relevant to PNS is now expanded to those against surface antigens. The organization of the collagen matrix and the distribution of CNTs revealed a spatio-temporal correlation between the presence of nanoheaters and the damages on collagen and cells. We therefore sought to identify small molecules that would enable testing of the hypothesis that positive modulation of CHT mediated transport would enhance activity-dependent cholinergic signaling.

clofranil tablets

Patient 1 was a 72-year-old man who presented with muscle soreness and elevated serum creatine kinase (CK) preceding an initial attack of NMO. Recovery of purified lactonic sophorolipids by spontaneous crystallization during the fermentation of sugarcane molasses with Candida albicans O-13-1. Our results confirm that overexpression of p53 protein is a common feature of esophageal and gastric carcinomas. Using flow cytometry, this study explored conditions that influence endovesiculation induced by chlorpromazine.

clofranil drug interactions

Dexamethasone intravitreal implant: an effective adjunctive treatment for recalcitrant noninfectious uveitis. All shunt valves were functioning properly at operative inspection but all patients were found to have adherent intracranial catheters with ingrowth of choroid plexus.

clofranil medicine bow

  • clofranil 10 side effects
  • clofranil drug
  • clofranil tablets for sale
  • clofranil medicine shoppe
  • clofranil medicine park
  • clofranil sr 75 mg wellbutrin
  • clofranil medicine cabinets
  • clofranil 50 mg zoloft
  • clofranil tablets best
  • clofranil medicine cabinet
  • clofranil sr 75 pill
  • clofranil tablets 10mg flexeril
  • clofranil tablets on sale
  • clofranil tablets for kids
  • clofranil clomipramine hydrochloride 50mg
  • clofranil tablets walmart
  • clofranil tablets under $100
  • clofranil medicine man
  • clofranil tablets 10mg melatonin
  • clofranil tablets 10mg diazepam
  • clofranil medicine dictionary
  • clofranil drug mart
  • clofranil clomipramine hydrochloride dogs
  • clofranil 75 mg wellbutrin
  • clofranil tablets side effects
  • clofranil tablets with keyboards
  • clofranil 25 mg uses
  • clofranil tablets
  • clofranil clomipramine hydrochloride for people
  • clofranil tablets at best
  • clofranil sr 75 mg benadryl
  • clofranil sr 75 mg zoloft
  • clofranil tablets 10 mg hydrocodone
  • clofranil 10 mg side effects
  • clofranil side effects
  • clofranil tab
  • clofranil tablets with usb
  • clofranil tablets with windows
  • clofranil drug interactions
  • clofranil drug interaction
  • clofranil clomipramine hydrochloride for humans
  • clofranil 50mg uses
  • clofranil tablets 10mg
  • clofranil 75 side effects
  • clofranil 10 mg uses
  • clofranil medicine for diarrhea
  • clofranil medicine wheel
  • clofranil medicine for anxiety
  • clofranil drug enforcement
  • clofranil drug testing
  • clofranil clomipramine hydrochloride
  • clofranil tablets 10mg ritalin
  • clofranil drug identification
  • clofranil 75 mg benadryl
  • clofranil tablets for toddlers
  • clofranil medicine ball
  • clofranil 50 mg demerol
  • clofranil 25 mg
  • clofranil clomipramine hydrochloride for dogs
  • clofranil tablets comparison
  • clofranil drug addiction

clofranil clomipramine hydrochloride

A genetically determined lack of oral tolerance to ovalbumin is due to failure of the immune system to respond to intestinally derived tolerogen. DNA double-strand breaks are lesions that form during metabolism, DNA replication and exposure to mutagens.

clofranil 75 mg benadryl

The optimal choice of implant addresses the stability of the fracture and affects the outcome. The human vitamin D receptor (hVDR) is a ligand-regulated transcription factor that mediates the actions of the 1,25-dihydroxyvitamin D3 hormone to effect bone mineral homeostasis.

clofranil 50 mg zinc

Early adversity and risk for moderate to severe unipolar depressive disorder in adolescence and adulthood: A register-based study of 978,647 individuals. The soluble-protein contents in the reproductive eggs laid by queen and workers and in the trophic eggs laid by workers are compared by disc electrophoresis.

clofranil tablets

We examined 19 patients, 16 of them with ovarian tumours, and attempted visualization of the uterine myometrium/endometrium as well as of the liver. To examine how Gata1 gene expression is regulated in a stage-specific manner, transgenic mouse lines expressing green fluorescent protein (GFP) reporter from the Gata1 locus in a bacterial artificial chromosome (G1BAC-GFP) were prepared.

clofranil tablets for children

In addition, increased tension, greater depression and fatigue, more frequent symptoms of CNS disturbances were observed in the exposed women compared to the controls. YEL-AND meningoencephalitis in a 4-year-old boy consecutive to a yellow-fever vaccine

clofranil drug testing

As in other investigated syllids, the proventricle region has a significant role during stolonization and reproduction processes in Typosyllis antoni. Exposure to phthalates (DEHP, DBP, and DIBP) at the examined concentrations induced behavioral defects, including changes in body bending, head thrashing, reversal frequency, and thermotaxis in C. Electrophoretic mobility shift assay revealed that TMS inhibited IL-1 beta-induced NF-kappa B activation, which is essential for E-selectin expression. Posttraumatic stress disorder as an insanity defense: medicolegal quicksand. Serum corticosterone and aldosterone were tested by ELISA, and mRNA expressions of cytokines in the adrenal gland were detected using Real-time PCR.

clofranil drug store

Under the same conditions of lactation, AVP mRNA content is not modified and the i.c.v. A copper wire intrauterine device (GuIUD) was inserted into mature female rabbits 14 days prior to artificial insemination (AI), and its effect on the histology of the pregnant uterus was studied 48 to 192 hours after AI. Although details of methods for sentinel lymph node biopsy have yet to be standardised, this technique is now widely practised and accepted as standard of care worldwide. The function of host discrimination and superparasitization in parasitoids.

clofranil 10 mg uses

Complexity in cognitive assessment of elderly British minority ethnic groups: Cultural perspective. The overall process can be completed within 2 h, starting from a CAD file, and can generate electrically continuous structures with the smallest dimension in the plane of the film of approximately 30 microns. Our results indicate that the nucleolar-associated human SUV3 protein is an important factor in regulation of the cell cycle. Leukotriene D4 facilitates airway smooth muscle cell proliferation via modulation of the IGF axis.

clofranil tablets 10 mg oxycodone

Between days 15 and 29 the risk of mortality was decreased for those with cemented THA (HR 0.7, CI 0.62 to 0.87). Likewise, cell death induced after NTN4 knock-down was rescued when NEO1 was transiently silenced, thus revealing an important role for NEO1 in NB cell survival. Recent advances in medical research suggest that the optimal treatment rules should be adaptive to patients over time. Calculations on the quantitative determination of the rate of turnover of a substance and their application to experiments involving the use of labeling agents are given. Ethanol only, or testing before ethanol administration, is not followed by tolerance.

clofranil clomipramine hydrochloride for people

Also, our result suggests that even finger joints contracted for 26 years can recover motion if they have not been directly damaged. In the first group the treatment was successful in 23 patients, and in 51 of the second group.

clofranil drug interaction

In this paper, changes of microstructural characteristics of disperse systems during mechanical activation of zinc oxide (ZnO) have been investigated. The article discusses difficulties associated with the definition of effective guidelines for their evaluation.

clofranil 10 mg

Exploring the self-learning experiences of patients with depression participating in a multimedia education program. Conditioned alimentary salivation reflexes in normal puppies and under conditions of thiamine deficiency Most clinicians from different subgroups studied followed a fairly similar order in the diagnosis of childhood pulmonary tuberculosis with a high premium placed on clinical features, bacteriologic, radiologic and therapeutic trial with anti tuberculosis drugs.

clofranil tablets 10mg melatonin

In this review, we provide an overview of our work and discuss the next steps, focusing on the potential clinical implications of these findings. Study of the Radial Peripapillary Capillary Network in Congenital Optic Disc Anomalies With Optical Coherence Tomography Angiography. Statistical performance of observational work sampling for assessment of categorical exposure variables: a simulation approach illustrated using PATH data. To study the role of endothelial NOS (eNOS) in vascular function, we disrupted the gene encoding eNOS in mice.

clofranil tablets comparison

Organization of electrical activity in the canine pyloric canal. Among 3 patients with an associated flexor tendon injury, 2 had excellent outcomes and one had a poor outcome. Combined, these results provide indirect evidence for independence in the neural control mechanisms underlying the two locomotive modes. Studies in clinical and community samples have documented that social anxiety disorder is common, disabling, and costly.

clofranil clomipramine hydrochloride for dogs

When used with the colony blot technique, MAb F6 was useful for detecting cross-reacting strains on plates of pure cultures or of mixtures containing nondegraders even when 2,4-D degraders were outnumbered 60 to 1. This paper demonstrates that the pattern of silver particles embedded in the gelatin matrix of exposed and developed silver halide-based photographic film can serve as a template in a broadly applicable method for the microfabrication of metallic microstructures.

clofranil drug addiction

Thus there is a need to develop statistically efficient approach for mining the underlying metabolite information contained by metabolomics data under investigation. Predicting accurate bond-length alternations (BLAs) in long conjugated molecular chains has been a major challenge for electronic-structure theory for many decades. Twelve healthy adult volunteers received intravenous fentanyl (15 microg/kg) or OTFC (three consecutive doses of 800 microg) on separate study sessions. Whereas DNA-bound p53 associates with JNK at G0-G1 and with Mdm2 and p300 during S and G2-M phases, the general pool of p53 was found in complex with JNK and Mdm2 almost throughout the cell cycle.

clofranil 75 mg benadryl

The studies were evaluated according to a modification of the methodological index for non-randomized studies (MINORS) criteria. The reason of the contrast enhance may be due presumably to protein transition from a soluble to a membrane-bound state.

clofranil drug testing

Utilization and toxicity of various iron compounds or complexes in iron-starved cells were assessed from the number of cell doublings obtained within a standard time. Microangiographic studies of the kidney of guinea pigs irradiated with fast electrons at 20 MeV

clofranil drug store

Autonomic imbalance, characterized by sympathetic hyperactivity and diminished vagal tone, is a known mechanism for essential hypertension. The effect of carbohydrates in milk on the absorption of calcium by postmenopausal women.

clofranil clomipramine hydrochloride dogs

Production and nucleotide sequence of an inhibitory human IgM autoantibody directed against platelet glycoprotein Ia/IIa. Direct interaction between miR-203 and ZEB2 suppresses epithelial-mesenchymal transition signaling and reduces lung adenocarcinoma chemoresistance.

clofranil tablets 2016

At ambient temperatures of 5, 15, and 25 degrees C tissue thermal conductance and cooling constant were significantly higher in clipped animals. The present study was designed to compare true digestible amino acid values for meat meal with available amino acid values. Improvements both in early and long-term follow-up care of cancer survivors seem warranted.

clofranil 75 mg equals how many ml

A new zeotype titanium silicate oxidation catalyst with the STT topology has been synthesized from direct synthesis. A diagnostic vitrectomy was performed on a patient with non-Hodgkin lymphoma who presented with a bilateral, rapidly progressing necrotizing retinitis and uveitis. In addition, parental representations at time 1 are significantly linked to particular personality characteristics at time 1 and 2. The diagnostic potential of the recombinant purified proteins was evaluated by immunoblot and enzyme immuno assays (EIA) using a total of 57 well-characterised serum samples obtained at various time points after natural RV infection, congenital rubella syndrome (CRS), MMR vaccination or from controls with past RV immunity.

clofranil drug information

The electron dynamics analysis reveals that a more efficient charge-carrier separation in the former can be obtained, the origin of which can be attributed to an increased number of surface defects in hexagonal WO3 nanoplates. No adverse events occurred intraoperatively and no failure in the intrathoracic esophagojejunostomy was observed, and favorable short-term results were obtained. Recently, the evolution of the primate and rodent Y chromosomes has been studied at the DNA level. Given the count nature of secondary crash frequency data, the authors used count modeling methods including the standard Poisson and Negative Binomial (NB) models and their generalized variants to analyze secondary crash occurrences.

clofranil 50mg vs 100mg

DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas. THE RECENTLY launched Department of Health national dementia strategy should be of interest to nursing managers, whether they are responsible for organising care for patients in hospital or in their homes. Neighborhood-level socioeconomic deprivation predicts weight gain in a multi-ethnic population: longitudinal data from the Dallas Heart Study.

 Show Hide 
clofranil sr 75 vs sr 2016-01-29

Both additional MIOLs performed well in terms of far, intermediate, and near vision and enabled patients to handle almost toxocariasis albendazole dosage for pinworm all areas of activity without glasses. Allocation of inner cell mass and trophectoderm cells to the preimplantation blastocyst of the domestic ferret, Mustela putorius furo. Surface-exposed adherence molecules of Streptococcus pneumoniae. Medical records of 686 patients admitted to Shohada hospital, Trauma Center of Tabriz University of Medical Sciences were reviewed.

clofranil tablets side effects 2015-05-05

This paper draws on official records of international and British organizations, newspaper reports, and volunteer memoirs to study the failure to protect humanitarian workers in the Second World War. Effect of biologically active plants used as netst material and the derived benefit to starling nestlings. The instrument used was a Laser Doppler Perfusion Monitor, Pf3 (Perimed, Stockholm, Sweden). The study of proBNP processing mechanisms is important, because processing impairments could be associated with the development of heart failure (HF). Thus, in this healthy group of subjects, there was no relationship between skin sumetrolim uk national lottery and bronchial reactivity.

clofranil side effects 2016-09-29

Limitations of traditional anticoagulants have led to the need for structured services to provide anticoagulation monitoring. The CFD results also show that, at least for flows involving high water vapour content, the axial velocity of the gas mixture at the mylan 40 mg omeprazole interface between the gas mixture and the condensate film is in general not small and cannot be neglected. Present status of gold in the treatment of rheumatoid arthritis. The findings are interpreted as further evidence of combined peripheral and central pathologic conditions in idiopathic trigeminal neuralgia.

clofranil tablets on sale 2010-07-22

The ultimate goal of cardiovascular nursing is to help patients achieve their optimal quality of life. A total of 119 patients with OSA received velopharyngeal surgery, including revised uvulopalatopharyngoplasty with uvula preservation and trisul tablets and alcohol transpalatal advancement pharyngoplasty. The usefulness of this approach for the study of arrhythmogenesis is discussed.

clofranil tablets at walmart 2014-09-01

The results obtained indicate that both terazosin hcl 5mg information MIP-1 alpha and LIF protect, at least transiently, the HSC repopulating ability in vivo in spite of the modest expansion in the number of nucleated and progenitor cells observed. The x-ray examination will indicate whether revascularization is feasible, although it cannot show whether it will be efficient. These stents promote laminar flow and depressurize the aneurysmal portion of the vessel, while preserving side branch vessel flow.

clofranil 25mg uses 2011-10-05

Main findings are that AIT can be effective in both monosensitized and polysensitized patients, as shown by large trials with grass extracts. Analysis of the defect in IFN-gamma induction of MHC class II genes in G1B cells: identification of a novel and functionally critical leucine-rich motif (62-LYLYLQL-68) in the regulatory factor X 5 transcription factor. From the data obtained by the various serological techniques, a tentative picture of the antigenic complex was formulated. Does lifestyle contribute to disease severity in patients with inherited cilift side effects forum lipid disorders?

clofranil 75 mg equals how many ml 2016-11-05

Both before (E8.5) and after (E11-adult) this brief period, staining with Rat-401 was absent from atrial and ventricular myocytes. Peptide Analysis and the Bioactivity of Whey Protein Hydrolysates from Cheese Whey with Several Enzymes. This article will focus on the mechanisms by which MSCs might exhibit a therapeutic potential in rheumatology. In contrast, cytoplasmic p50, p65, c-Rel as well allopurinol normon 100 mg precio del as IkBalpha remained intact after MCG treatment, although p52 was clearly degraded.

clofranil sr 75 mg equals how many ml 2013-03-15

By the computational analysis of the predicted amino acid sequences against the OWL and Pfam databases, 58 predicted gene products were classified into the following five functional erythromycin eye ointment for infants categories: cell signaling/communication, cell structure/motility, nucleic acid management, protein management and metabolism. Controls were matched to cases according to gestational age and birth weight. The goal of this research was to compare the demographics, clinical characteristics and treatment patterns for newly diagnosed multiple sclerosis (MS) patients in a commercial managed care population who received disease-modifying drug (DMD) therapy versus those not receiving DMD therapy. Further studies are still needed to confirm the benefit of this approach over conventional surgery for PHC. These data suggest a close interplay of HrrSA and ChrSA at the level of transcription and emphasize ChrSA as a second TCS involved in haem-dependent gene regulation in C.