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Buspin (Buspirone)

Buspin is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, Buspin is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, Buspin does not exhibit anticonvulsant, sedative, hypnotic, and muscle-relaxant properties. Due to these characteristics, Buspin been termed 'anxioselective'. First synthesized in 1968 then patented in 1975, it is commonly marketed under the brand name Buspin. Buspin was first approved in 1986 by the FDA and has been used to treat anxiety disorders, such as generalized anxiety disorder (GAD), and relieve symptoms of anxiety. It has also been used as a second-line therapy for unipolar depression when the use of selective serotonin reuptake inhibitors (SSRIs) is deemed clinically inadequate or inappropriate. The potential use of Buspin in combination with melatonin in depression and cognitive impairment via promoting neurogenesis has also been investigated.

Other names for this medication:
Buspirone, Buspar, Ansial, Ansitec, Ansiten, Anxinil, Anxiron, Bespar, Busansil, Busirone, Buspin, Buspiron, Buspirona, Ledion, Narol, Neurosine, Paxon, Sorbon, Spamilan, Spitomin,

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Induction of substance P-immunoreactivity by estrogen in neurons containing estrogen receptors in the anterovental periventricular nucleus of female but not male rats. Determination of axis of femoral anteversion in proximal femur has been the subject of debate in the literature.

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a statistically non-significant decrease was observed in the percentage of embryos under the optimal cleavage curve on D3 in the group of men aged between 40 and 45 years. Extraction from prawn shells of substances cryoprotective for Vibrio cholerae. Two patients with a remote history of pathologically documented giant cell arteritis developed severe regurgitation.

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Non-invasive prenatal testing offered as part of a combined first-trimester screening program identifies tetrasomy 18p in a high-risk pregnancy. The latter three antibodies were found to specifically recognise PRLR. However, both 19-hydroxyandrostenedione and 19-oxoandrostenedione competitively inhibited aromatization of androstenedione, and all three steroids were shown to be mutually competitive.

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Biosynthesis of alkaline phosphatase in cultures of Pseudomonas fluorescens. Thermal and energetic processing of ammonia and carbon dioxide bearing solid mixtures. The complexation of the CpFe(CO)2 (Fp) pendent group with cyclodextrin (CD) molecules created air-stable poly(Fp-methylstyrene) P(CD/FpMSt). Fresh frozen plasma use in the NICU: a prospective, observational, multicentred study.

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A reduction in SI distinguishes ALS from mimic disorders, potentially facilitating an earlier diagnosis of ALS. Described herein are variants of the clinical pattern and possible complications, with an emphasis placed on methods of diagnosis and differential diagnosis of tumour-like neoplasms in the infragenicular region. Although there is a growing recognition of the importance of active communication behaviours from the incoming clinician receiving a patient handover, there are currently no agreed-upon measures to objectively describe those behaviours. Cranial computerized tomographic scans were performed during the period of respirator treatment within the first week of life. A substantial body of literature has accumulated during the past 20 years showing the plasma concentrations of 5-fluorouracil (5-FU) to correlate with clinical response and/or toxicity in colorectal cancer, and head and neck cancer, but little information is available concerning effects on long-term survival.

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On the thermodynamics of particle-stabilized emulsions: curvature effects and catastrophic phase inversion. The main advantage of this procedure was that the small operative scars improved the cosmetic results. We have constructed a model of child dental fear which helps us in our work. Demonstration of an ultra-high frequency picosecond pulse generator using an SBS frequency comb and self phase-locking.

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We conducted two experiments to determine how resource availability influenced allocation by tomato (Lycopersicon esculentum) to trichomes, and how different patterns of trichome allocation by plants grown in different resource environments might then influence the behavior of tobacco hornworm (Manduca sexta) caterpillars. Feedback on sterol synthesis was evidenced by elevated levels of cellular sterols in treated vs. Second-look arthroscopy was performed in 13 hips in 12 patients. There is high unmet prosthetic care for non-institutionalised elderly population in Aluva. faecium strains but had no effect on the growth of strains of other species of enterococci.

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A total of 50 unrelated OFX mono-resistant MTB isolates were analyzed. The role of inflammation resolution speed in airway smooth muscle mass accumulation in asthma: insight from a theoretical model. Sorption kinetic results show that the adsorbent size influenced greatly the sorption velocity, and both the GAC and AI400 required over 168h to achieve the equilibrium, much longer than 4h for the PAC. The influence of MHC polymorphism on the selection of T-cell determinants of FMDV in cattle.

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Urinary bone resorption markers and QUS are equally discriminatory between non-vertebral fracture patients and controls. Another important advantage they offer is that they do not need replacement as frequently as double J catheters or nephrostomy tubes require.

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The aims of this study were to examine the relation of intestinal and diffuse types of gastric cancer to the atrophic border and to study the pathologic condition of the atrophic border. The potential distribution underlying the anticipatory attention for the KR stimulus suggested a right hemisphere network in which the prefrontal cortex, the insula Reili and the parietal cortex were involved. Work stressors, sleep quality, and alcohol-related problems across deployment: A parallel process latent growth modeling approach among Navy members.

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Promoting mental health: recent progress and problems in Australia. Recognition of the class Ib molecule Qa-1(b) by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells.

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Genetic and environmental influences on airway inflammation in asthma. A personal viewpoint and philosophy concerning the surgical treatment of duodenal ulcer. Initial management is conservative, with the goal of providing relief from pain and swelling. This report highlights ascites as a previously unrecognized adverse reaction to sorafenib in a patient with a ventriculo-peritoneal shunt. Contrary to previous findings Asians were more likely to have had longer duration of symptoms prior to seeking help.

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We used an optical system and 9 SLMs to construct a device equivalent to an SLM with approximately 74,600,000 pixels and used this to reconstruct 3D objects in both the horizontal and vertical parallax with an image size of 63 mm without losing any part of 3D objects. All the class mu enzymes mediated preferential glutathione conjugation of (R)-STO to (S)-STO. Although a right-video-assisted thoracoscopy was considered the gold standard in this clinical setting to achieve a tissue acquisition of the pleura, an EUS (as the least invasive procedure) was attempted to reach a definitive diagnosis. HCV RNA detection in HCV antibody-positive patients with the COBAS AmpliPrep/COBAS TaqMan HCV test, v2.0 in comparison with FDA-approved nucleic acid tests. According to the 2000 Census, about 1.2 million persons over age 50 are currently cohabiting.

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Effect of hydrophobic bile acids on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and mRNA levels in the rat. Increasing the ionic strength of the solution also improves the chaperone activity of full-length HTLV-1 NC. In particular, factors influencing the suppression of ignored visual stimuli were investigated.

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European Hernia Society guidelines suggested that the evidence of mesh augmentation for the prevention of incisional hernia (IH) was weak. Given this fact, one would think it logical that data are analyzed with the appropriate statistics on the log-scale and not by summary statistics, such as arithmetic means, on the original scale. This study was a single-center, cross-sectional analysis of patients who were seen by a clinical pharmacy specialist (CPS).

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The reaction of 2CP with singlet oxygen (type II of photooxidation) appeared the most important pathway of degradation. The relationship between diet, nutrition and dental health: an overview and update for the 90s. Genetic loci or genes have been identified for Carney complex, Peutz-Jeghers and Ruvalcaba-Myhre-Smith syndromes, but not for other lentiginoses. The survival range from pulmonary recurrence of HCC was 7.5 to 43.0 months and the median survival time was 18.9 months. A prospective longitudinal study evaluating the usefulness of the interferon-gamma releasing assay for predicting active tuberculosis in allogeneic hematopoietic stem cell transplant recipients.

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Telomeres protect the chromosome ends from degradation, end-to-end fusion and abnormal recombination and they also promote the end replication. Cross-reactivity in fluorescence tests for Trypanosoma and Leishmania antibodies. To better understand the SCF and dexamethasone effect, PGHS-I and PGHS-II mRNA expression were examined by Northern analysis.

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This study found no evidence to suggest that a selective breeding programme based on PrP genotype will have a detrimental effect on lamb survival. Deaths that potentially could be avoided if patients with conditions for which a mortality-volume relationship had been treated at an HVH vs LVH. A bronchopleural fistula then recurred, after which it was treated by conservative therapy including intravenous hyperalimentation, frequent dressing changes and systemic administration of appropriate antibiotics.

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Thus, our study reveals that Miz-1 acts as a p53 suppressor by interfering with p53 DNA-binding ability, and ARF is able to counteract the suppression of Miz-1 on p53 by direct binding to Miz-1, suggesting that Miz-1 is a novel mediator in the ARF-p53 pathway. Axonal and dendritic transport in Purkinje cells of cerebellar slice cultures studied by microinjection of horseradish peroxidase. The researchers conclude that the Persian version of the FOUR score is a reliable and valid scale to assess unconscious patients with traumatic brain injury and can be substituted for the GCS. Multiple regression analysis was performed using 9 variables related to pulmonary gas exchange, to identify those which were important. Detection of alpha 6, the laminin binding receptor subunit, was expressed most intensely along the basal side of basal cells in a normal cornea.

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Another key to successful live-cell imaging is to minimize light exposure as much as possible. Furthermore, a significant positive correlation was found between augmenting evoked potentials and Overt Hostility Outward scores.

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Our results suggest that the effect of exercise on relieving menstruation pain increases over time. The risk of recurrent ischemic and hemorrhagic stroke was greater in Asians with high blood pressure.

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In contrast, many substitutions, including those of charged and bulky residues, disrupted folding of full-length CFTR in cells. This paper highlights some of the findings from a recent study with women community mental health nurses which explored the relationship between emotional wellbeing and professional practice.

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Available data indicate that pneumococcal conjugate vaccines (PCVs) are effective in children, reducing all-cause CAP cases and bacteremic and nonbacteremic CAP cases. was isolated in a mixed culture with Escherichia coli and probably represents the first human isolate of P.

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In present studies, effects of soil N fertility on aboveground N pools and production were examined, and the N: P stoichiometry was compared among forbs, graminoids, and legumes on an alpine grassland located in northeast of Qinghai-Tibet Plateau. Thus, leukocytes from the rheumatoid patients responded differently from surgical trauma when compared with leukocytes from the arthrosis patients. However, systematic evaluation of all associated diseases in children with FMF has not been done previously. A meta-analysis of operative blood loss showed a highly significant drop in operative blood loss in breasts infiltrated with epinephrine and a reduction in the need for blood transfusion.

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Bony defects of the glenoid may be caused by a fracture or due to chronic wear (fracture or erosion type). Magnesium deficiency may result in hypokalaemia, hypocalcaemia or other disturbances of electrolyte homeostasis, refractory cardiac arrhythmias, or increased sensitivity to digoxin. Activated peptides are potential modulators of various regulatory processes in the living system: immunomodulatory peptides stimulate the activities of cells of the immune system and several cytomodulatory peptides inhibit cancer cell growth, antimicrobial peptides kill sensitive microorganisms, angiotensin-I-converting enzyme (ACE)-inhibitory peptides exert an hypotensive effect, opioid peptides are opioid receptor ligands which can modulate absorption processes in the intestinal tract, mineral binding peptides may function as carriers for different minerals, especially calcium. The majority of included studies were conducted in the United States (US), with significant heterogeneity in terms of policy level (e.g., national, state) studied, areas of focus, and methodologies used. Responses of macaque perirhinal neurons during and after visual stimulus association learning.

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A new flavone, wightianin (1), along with five known compounds, n-triacontanol (2), betulinic acid (3), oleanolic acid (4), 3,4-O-isopropylidene-shikimic acid (5), and isoquercitrin (6), were isolated from the whole plants of Hypericum wightianum Wall ex Wight et Arn. Of 16 patients with anterior spinal tuberculosis treated in this unit during the period 1979-1984, five presented with neurological complications following laminectomy at another hospital. DDN in active myofascial trigger points (MTrPs) in the upper trapezius. In this tutorial, selected phonetic symbols and phonetic phenomena are reviewed. A simple preparation of pyridine-derived N-heterocyclic carbenes and their transformation into bridging ligands by orthometalation.

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The neuronal death that accompanies an ischemic stroke has previously been attributed to a necrotic process. Human migrating myoelectric complex in relation to gastrointestinal transit of a meal. Thrombomodulin (TM), a potent anticoagulant, is not detected in quiescent vascular smooth muscle cells (VSMCs). Our results demonstrate that force-resistant attachment enables a stark tension increase in the myotendinous system. Herein, we investigated the therapeutic potential of valproic acid (VPA) on optic neuritis in experimental autoimmune encephalomyelitis (EAE), a mouse model of MS.

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We describe the late presentation of such a case and discuss the possible mechanism of injury. ATase brings about the short-term regulation of glutamine synthetase (GS) by catalyzing the adenylylation and deadenylylation of GS in response to signals of cellular nitrogen status and energy.

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The risk of development of hepatocellular carcinoma (HCC) in hepatitis B virus (HBV) and hepatitis C virus (HCV) infection is well established and is being recognized increasingly in non-alcoholic steatohepatitis (NASH)-related cirrhosis. Blood-forming cells are present in the fetus or pup livers during this period. And others such as pre-operative bridging therapy for liver transplantation, adjuvant therapy for hepatic resection and combination of local and regional therapies have also shown some benefits in preliminary results, which need confirmation in further studies. Total number of mosquitoes increased each year during the study.

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Although patients with AML achieve complete remission at high rates, the long-term prognosis for such patients remains unsatisfactory. Interestingly, we found that the universal degenerated primers also amplified the chromosomally located K1-gene in all 34 K.

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Atrophy of the ileal epithelium within the gnotobiotic group and within the Thiry-Vella loops was observed, possibly secondary to an altered endogenous microbial flora. In the past decade, it has been extensively shown that mesenchymal stem cells (MSCs) have a wound healing potential. This study provides the first evidence that predator cues perceived by females early in life positively affect egg mass, suggesting that these cues allow her to predict the predation risk for her offspring.

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Estimated ventricle size using Evans index: reference values from a population-based sample. It has been successfully used for the treatment of several viral infections including labial and genital herpes. The European Society of Thoracic Surgeons (ESTS), the most representative society of general thoracic surgeons in the world, established a dedicated thymic working group in 2010 with the intent to provide a platform among ESTS members with a specific interest in thymic malignancies. In dealing with this overlap, we found that only early age at onset, or major depression with an anxiety disorder or secondary alcoholism, were independently related to increased risk of major depression in relatives.

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Genetic polymorphisms of the CETP gene can influence levels of serum lipoproteins. A mutant of SPO2, SPO2ehp4-, lysogens of which no longer interfere with the development of SP82GIs, was also isolated. Visible-light activity enhancement of gold-nanoparticle-loaded titanium(IV) dioxide by preferential excitation of localized surface plasmon resonance. The 43.1-kDa tetracycline-cation/proton antiporter TetA from Tn10 comprises two equal-sized domains, alpha and beta (amino-terminal and carboxyl-terminal halves, respectively).

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Distributed patterns of occipito-parietal functional connectivity predict the precision of visual working memory. The chemical and enzymatic dissociation of the specific antigen of Type Z Shigella paradysenteriae has been studied. To evaluate PCO and the position of the anterior capsulorhexis, retroillumination digital photographs were taken 5 years postoperatively and analyzed using the POCOman computer-analysis system. Anatomical location and somatotopic organization of the corticospinal tract in the corona radiata of the normal human brain: a diffusion tensor tractography study.

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Results indicated that reactivation makes episodic memories susceptible to physiological and behavioral interference. P-glycoprotein expression was evaluated by immunoblot using the JSB-1 and C219 monoclonal antibodies. Acute hemorrhagic encephalomyelitis (AHEM) is considered a rare form of ADEM. The IL23R region was also linked to celiac disease in Finnish families, but no association of IL23R variants with celiac disease was found in the Finnish, Hungarian or Italian samples. ISIP and the low use of condoms, particularly with steady partners, could be a contributory factor to the spread of HIV, hepatitis C virus, and hepatitis B virus infection.

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However, molecular hybridization experiments revealed nucleotide sequences homologous to nucleic acids of oncornavirus of D-type in milk obtained from breast carcinoma patients as well as in milk of healthy donors. The level of free adenine in thymocytes and spleen T-lymphocytes during tumour growth showed a 2-4-fold increase in comparison with normal values. Within unemployed samples, work-role centrality, coping resources (personal, social, financial, and time structure), cognitive appraisals, and coping strategies displayed stronger relationships with mental health than did human capital or demographic variables. The cytokines granulocyte colony-stimulating factor, erythropoietin, and stem cell factor may play a role in helping to stimulate cell regeneration under normal physiologic conditions and in patients with myocardial injury.

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Here, a global analysis of fungal gene expression using the Affymetrix Fusarium GeneChip during culture under DON-inducing conditions compared with noninducing conditions is reported. Interleukins 1 and 6 may play stopping remeron medication mirtazapine a role in the pathogenesis of the lesional lymphocyte infiltrates in mycosis fungoides.

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Two strains, CNP330 and CNP334, were studied and found to harbour various plasmids but all attempts to cure trimethoprim resistance were unsuccessful. Long-term efficacy of induction mycoderm powder composition meaning therapy with anti-interleukin-2 receptor antibodies or thymoglobulin compared with no induction therapy in renal transplantation.

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Of gastrex 4600 reviews the dysplasias, 20 were from an ongoing longitudinal study showing progression. Hearts were sampled at defined periods for microvascular expression of P-selectin, identified by immunohistochemistry.

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However, its usefulness metrogyl gel usagencies has been limited by the requirement for the DNA to be cloned onto an appropriate vector. Polycomb-repressive complex 2 (PRC2) comprises specific members of the Polycomb group of epigenetic modulators.

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GH74 endo-xyloglucanases cleave xyloglucan backbones with unsubstituted glucose at the -1 subsite metrozole stomach medicine or prefer xylosyl-substituted residues in the -1 subsite. To further decrease genotyping effort and rapidly screen for tightly linked markers, we propose here a combined DNA pooling and SRG strategy. This prevented expression of certain endometrial receptivity genes, perturbed uterine fluid handling and abolished embryo implantation. Blastocyst trophoblast expressed receptors for all the lectins but later tissues of the trophectoderm lineage lost receptors for distinct but overlapping subsets of the lectin panel.

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Lab and pilot scale batch cultivations of a CHO K1/dhfr(-) host cell line were conducted to evaluate on-line multifrequency permittivity measurements as a process monitoring tool. Furthermore, carnosine could reduce the phosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2) and p38 mitogen-activated protein kinase (p38 MAPK). oprazole and common side effects This article is intended to provide a summary on the development and degradation of aroma of selected major fruits and vegetables, 20 in each category. Quantitative map analyses based on statistical representation of maps by coefficients and common basis functions have been developed.

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The findings in a highly selected group of patients, such as those attending clinics or sanatoria, cannot be used as the basis for assessing the true prevalence of strains of Mycobacterium tuberculosis with acquired or primary resistance or of sensitive strains in a community. The hypoxia-inducible factor (HIF) couples immunity with metabolism. In some clinical situations, the length of either a prepared tooth or an implant abutment is shorter than ideal, and the thickness of a porcelain crown must be increased. There have been persistent claims that the contingent negative variation prevas medicine bow (CNV) is absent or greatly attenuated in psychopaths. Prospective studies should be performed to determine the optimal anticoagulation regimen.

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After receptor binding, changes in chromatin structure are detected that correlate with binding of transcription factors, including nuclear factor I, to the MMTV promoter. This is a descriptive study, from January 2003 until December 2007. Direct-to-consumer advertising for oral cancer screening devices. This article discusses axillary ultrasonography for axillary staging relative to neoadjuvant chemotherapy, reviews advances in sentinel lymph amodex ink and stain remover uk lottery node (SLN) biopsy techniques, and explores an integrated approach to axillary staging. One or both parents of nine of the children had AIDS or risk factors for AIDS.

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Immunohistochemistry was used to define HVEM expression in the cornea and TG of normal and HSV-1 infected mice euthanized 2 to 5 days or 7 months following corneal inoculation of virus. We have established improved conditions for separating the chromosomes of Plasmodium falciparum by pulsed field gradient gel electrophoresis (PFG) using a contour-clamped homogenous electric field (CHEF) metronidazole pregnancy risk category drug apparatus. Learning to eat vegetables in early life: the role of timing, age and individual eating traits. Human fgl2 (hfgl2) gene expression was determined in the PBMCs by real-time PCR.